. 1999 Feb 15;515(Pt 1):61–73. doi: 10.1111/j.1469-7793.1999.061ad.x

Table 2.

Kinetic parameters of slow inactivation for hH1, μ1 and hH1-μ1 chimaeras

	Development of slow inactivation		Recovery from slow inactivation		Steady-state slow inactivation (δ_∞)

Channel	τ₁ (s)	τ₂ (s)	τ₁ (s)	τ₂ (s)	V_1/2 (mV)	Slope (k)
hH1	6.9 ± 0.6(11)^†	52.0 ± 5.9(11)	0.54 ± 0.1(6)^†	12.1 ± 3.0(6)^†	−78.3 ± 2.8(6)^†	23.1 ± 2.5(6)^†
	35%^†	30%^†	48%^†	14%
μ1₍₁₎hH1_(2,3,4)	6.0 ± 0.7(8)^*^†	87.5 ± 8.9(8)^*^†	0.52 ± 0.1(8)^†	14.1 ± 2.6(8)^†	−60.8 ± 1.4(10)^*^†	18.8 ± 1.2(10)^*^†
	60%^*	15%	50%^†	17%
μ1_(1,2)hH1_(3,4)	1.6 ± 0.1(8)^*	53.8 ± 18.7(8)	0.72 ± 0.2(6)^*	15.2 ± 7.1(6)^†	−62.9 ± 0.6(6)^*^†	10.4 ± 0.6(6)^*
	73%^*	11%	69%^*	19%
μ1_(1,2,3)hH1₍₄₎	1.3 ± 0.1(10)^*	65.6 ± 17.0(10)	0.89 ± 0.1(8)^*	14.5 ± 4.8(8)^†	−87.9 ± 0.3(8)^*^†	9.5 ± 0.3(8)^*
	73%^*	16%^*	66%^†	23%^*^†
μ1	1.6 ± 0.1(10)^*	39.4 ± 10.9(10)	1.0 ± 0.1(10)^*	34.0 ± 8.3(10)^*	−73.1 ± 1.1(8)^*	10.3 ± 0.8(8)^*
	80%^*	10%^*	72%^*	19%

V_1/2 and k for steady-state slow inactivation (s_∞) were obtained from a Boltzmann fit of the mean data. Time constants (τ₁ and τ₂) were obtained with a double exponential fit of the mean data. Data are presented as means ± s.e.m. (n), where n is the number of cells. The percentage values are the percentage component of the curve described by the exponential.

P < 0.05 vs. hH1

^†

P < 0.05 vs. μ1.