Table 2. Lung mechanics: lactic acid/atropine study.
| Raw baseline values | Maximum response | |||
|---|---|---|---|---|
| Lactic acid(0.4 mmol kg−1) | RL(cmH2O ml−1 s) | EL,dyn(cmH2O ml−1 s) | RL(% change) | EL,dyn(% change) |
| 0.2 ml injectate | ||||
| Saline | 0.093 ± 0.010 | 0.821 ± 0.08 | 1.5 ± 1.1 | 1.7 ± 0.4 |
| Intact | 0.097 ± 0.0003 | 1.353 ± 0.002 | 51.6 ± 6.7* | 31.7 ± 2.6* |
| Post-atropine | 0.084 ± 0.001 | 1.398 ± 0.002 | 30.9 ± 3.9† | 26.4 ± 4.6 |
| 0.4 ml injectate | ||||
| Saline | 0.101 ± 0.008 | 0.779 ± 0.117 | 3.2 ± 2.0 | 0.1 ± 0.2 |
| Intact | 0.100 ± 0.001 | 1.171 ± 0.004 | 49.2 ± 10.9* | 25.0 ± 4.5* |
| Post-atropine | 0.091 ± 0.001 | 1.210 ± 0.004 | 10.6 ± 4.0† | 13.9 ± 4.0 |
RL, inspiratory lung resistance; EL,dyn, dynamic lung elastance.
Significantly different from saline (P < 0.05)
significantly different from intact (P < 0.05). Values are means ± S.E.M.