Figure 2. Effect of ATP concentration on the volume-sensitive anion conductance in non-swollen rat β-cells.

Outward (I₊₁₀₀) and inward (I_-100) current densities in response to voltage pulses of +100 and -100 mV, respectively: effects of increasing concentrations of Mg²⁺-ATP. The pipette solutions were maintained slightly hypotonic (265 mosmol l⁻¹) in order to prevent cell swelling. All values represent maximum currents attained in each cell. The values in parentheses represent the number of cells for each treatment. *P < 0.05, between the groups as shown; n.s., P > 0.05.