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. 1999 Mar 1;515(Pt 2):413–417. doi: 10.1111/j.1469-7793.1999.413ac.x

Figure 4. Effect of GTPγS and GDPβS on the volume-sensitive anion conductance in rat β-cells.

Figure 4

Outward (I+100) and inward (I-100) current densities in response to voltage pulses of +100 and -100 mV, respectively: effects of 2 mM ATP, 2 mM ATP + 0.1 mM GTPγS, 2 mM ATP + 2 mM GDPβS and 2 mM GTPγS alone. The pipette solutions were maintained at constant hypertonicity (305 mosmol l−1) in order to induce cell swelling. All values represent maximum currents attained in each cell. Each bar represents the mean ±s.e.m. of 4-5 separate determinations. *P < 0.05 compared with 2 mM ATP alone (column 1).