Figure 2. cpt-cAMP reduces the activation of an outward potassium current.

A, time-dependent suppression of I_K after exposure to 100 μM cpt-cAMP. Currents were obtained in response to incremental 10 mV steps from a holding potential of -60 mV. B illustrates the currents shown in A after they were converted to conductance (G) values and fitted by the Boltzmann relation as described in the Methods section. In A and B, each point represents the mean ±s.e.m. from ten neurones. For those points appearing to lack error bars, the size of the bar is smaller than the symbol.