Figure 9. The effects of TEA or 4-AP and cpt-cAMP on I_K at the -30 mV conditioning prepulse voltage.

These representative current traces illustrate the effects of either TEA or 4-AP and 100 μM cpt-cAMP in the presence of TEA or 4-AP. A shows currents obtained under control conditions from a prepulse of -30 mV (top). The middle panel represents the suppression of these currents by 10 mM TEA. The bottom panel shows the currents remaining after a 20 min exposure to cpt-cAMP in the presence of 10 mM TEA. B illustrates the effects of 4-AP, where the top panel shows the currents obtained under control conditions from a prepulse of -30 mV. The middle panel represents the suppression of these currents by 1 mM 4-AP. The bottom panel shows the currents remaining after a 20 min exposure to cpt-cAMP in the presence of 1 mM 4-AP. The calibration bar for time is the same for all six panels.