Table 1.
V0.5 (mV) | k (mV) | G/Gmax | ||
---|---|---|---|---|
Control† | 4 ± 2 | 17 ± 1 | 1.0 | |
cpt-cAMP | 2 min | 7 ± 2 | 18 ± 1 | 0.92 ± 0.02* |
6 min | 7 ± 3 | 18 ± 1 | 0.85 ± 0.04* | |
10 min | 6 ± 2 | 17 ± 1 | 0.76 ± 0.03* | |
20 min | 5 ± 2 | 17 ± 1 | 0.69 ± 0.02* | |
Control† | 1 ± 2 | 14 ± 1 | 1.0 | |
PGE2 | 2 min | 1 ± 2 | 15 ± 1 | 0.90 ± 0.02* |
6 min | 1 ± 3 | 15 ± 1 | 0.81 ± 0.03* | |
10 min | 2 ± 3 | 15 ± 1 | 0.73 ± 0.03* | |
20 min | −1 ± 3 | 16 ± 1 | 0.64 ± 0.05* | |
Control + PKI‡ | 5 ± 2 | 15 ± 1 | 1.0 | |
PGE2+ PKI | 20 min | 5 ± 2 | 17 ± 1 | 0.97 ± 0.05 |
Values are means ± S.E.M.
Significant difference from respective controls
n = 10
n = 7.