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Simultaneous measurements of changes in isometric force (upper traces) and NO concentration (lower traces) in an endothelium-intact segment of rat superior mesenteric artery. A, acetylcholine (ACh, 3 μM) was added with the preparation at resting tension; B, ACh was added with the preparation contracted with 1 μM noradrenaline (NA). W, washout. The traces are representative of 4 experiments.
