Figure 2. Glucose induces different fluorescence signals in individual cells.

A, changes in fluorescence induced by decreasing glucose concentrations in cells 1 and 2. The bars above the traces indicate the periods of application of different glucose concentrations. B, frequency of [Ca²⁺]_i oscillations (ν) vs. glucose concentration for cells with the [Ca²⁺]_i pattern of cell 1 (•), cell 2 (○) and cells with typical β-cell synchronous [Ca²⁺]_i oscillations (▴). Points are the mean of 16 cells from 5 different islets. C, percentage of time that [Ca²⁺]_i remained elevated vs. glucose concentration in the same cells as B; same symbols.