Figure 2. Comparison of the time course of current traces for α_1C and α_1CY467S expressed without or with β_1a, β_2a or β₃ in tsA201 cells.

The membrane potential was stepped for 400 ms from a holding potential of -80 mV to 0, +20 or +40 mV (upper, middle and lower traces, respectively). The magnitude of currents varied greatly between individual cells (see also error bars in Fig. 3A and B). Current inactivation was slowed down on coexpression of α_1C or α_1CY467S with β_2a. There was no apparent difference between currents recorded from α_1C- or α_1CY467S-transfected cells.