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. 1999 Jun 15;517(Pt 3):771–779. doi: 10.1111/j.1469-7793.1999.0771s.x

Figure 4. Specificity of the responses to V1a and V2 receptor agonists.

Figure 4

The [Ca2+]i transient elicited by F-180 (1 μm) was totally blocked by 10 nm of the specific V1a receptor antagonist (SR 49059, A), but was maintained in the presence of 10 nm V2 receptor antagonist (SR 121463A, B). Similarly, response to dDAVP (1 μm) was abolished after pre-incubation with 10 nm SR 121463A (C) but persisted in the presence of 10 nm SR 49059 (D). A and B show the reversibility of the blockade induced by each antagonist.