Figure 2. Effects the glucocorticoid receptor antagonist RU38486 on the incidence of circular walking in avertin-UL animals.

□, control group, n = 12 animals; ▪, RU38486 treated group, n = 12 animals. The number of circular movements carried out by the labyrinthectomized animals over a 3 min period when placed in an open enclosure, were measured at hourly intervals after recovery from avertin anaesthesia. The bars show the mean (±s.e.m.) number of circular walks for the two groups at each time point. Asterisks indicate a significant difference between the RU38486-treated and control groups (P < 0.05, Mann-Whitney ranked sum test).