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. 1999 Jul 15;518(Pt 2):417–432. doi: 10.1111/j.1469-7793.1999.0417p.x

Figure 2. The effect of NPPB on single channel currents through 4 pS amiloride-sensitive Na+ channels in cell-attached patches.

Figure 2

A, actual traces of single channel currents in the absence (a) and presence (b) of NPPB (200 μM) in the pipette solution obtained from cells 150 min after exposure to a hyposmotic solution. Even in the presence of NPPB in the pipette, the channel showed activity similar to that in the absence of NPPB. B, statistical results of the open probability (Po) of the channel in the absence (Inline graphic) and presence (▪) of NPPB (200 μM) in the pipette solution. NPPB had no significant effect on the open probability of the channel. n = 8. C and dashed line represent the closed level of the channel.