Figure 8. Time courses of conductance under various conditions.

A, control. B, DPC (2 mM, bilateral application) decreased the basal conductance. Nystatin (50 μM, apical application) had a small effect on the conductance. NPPB decreased the conductance a little bit. C, in a Cl⁻-free gluconate solution, nystatin induced a small increase in conductance. NPPB decreased the conductance a little bit. D, in a Cl⁻-free NO₃⁻ solution, nystatin drastically increased the conductance, identical to control. NPPB also markedly inhibited the increased conductance similar to control. n = 4-6.