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. 1999 Sep 1;519(Pt 2):571–579. doi: 10.1111/j.1469-7793.1999.0571m.x

Table 3.

Cardio-respiratory responses during repetitive hypoxia: number of exposures to hypoxia

Quiet sleep Active sleep


1–10 11–20 21–30 31–40 1–10 11–20 21–30 31–40
ΔV (%) 144 ± 30 140 ± 35 131 ± 21 146 ± 41 88 ± 15 39 ± 10 50 ± 9 41 ± 9
ΔA (%) 73 ± 16 74 ± 21 68 ± 15 83 ± 29 50 ± 12 25 ± 8 34 ± 7 30 ± 8
Δf (%) 37 ± 5 34 ± 4 36 ± 4 36 ± 6 20 ± 4 12 ± 3 13 ± 4 9 ± 4
ΔBP (%) 3 ± 1 3 ± 1 3 ± 1 3 ± 1 5 ± 1 0 ± 1 4 ± 1 2 ± 2
ΔHR(%) 4 ± 1 3 ± 1 2 ± 1 4 ± 1 −3 ± 1 −2 ± 2 0 ± 1 −2 ± 2
Sp,O2(%) 84 ± 2 85 ± 2 87 ± 2 87 ± 2 82 ± 2 83 ± 2 81 ± 2 81 ± 3

Values are means ±s.e.m., n = 9 lambs. Values are expressed as a percentage change from normoxia for the following: ΔV, change in ventilation; ΔA, change in respiratory amplitude; Δf, change in respiratory frequency; ΔBP, change in mean arterial blood pressure; ΔHR, change in heart rate. Sp,O2, pulse oxygen saturation.

P <0.05, value vs. 1–10 exposures (ANOVA and Student-Newman-Keuls post hoc test).

P < 0.05, value vs. normoxia (ANOVA and Student-Newman-Keuls post hoc test).