Figure 9. Effects of transjunctional voltage (V_j) on single channel activity.

Long-lasting segments of current records obtained from a cell pair with a single operational gap junction channel. The signals were recorded during steady-state conditions. Upward deflections correspond to channel openings. When V_j was increased from 25 to 35, 40 and 55 mV (from top to bottom), the channel spent progressively less time in the main state and more time in the residual state (dashed lines). Continuous lines refer to the zero coupling current.