Table 1.
Alterations in the voltage dependence of SR permeability and intramembrane charge movement induced by 3 mm perchlorate or 1 mm caffeine
| SR permeability | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Peak | Steady level | Intramembrane charge | |||||||
| Pmax(% ms−1) | V′(mV) | k(mV) | Pmax(% ms−1) | V′(mV) | k(mV) | Qmax(nC μF−1) | V′(mV) | k(mV) | |
| Reference | 1.36 ± 0.11 | −4.6 ± 2.2 | 8.6 ± 0.8 | 0.50 ± 0.06 | −9.0 ± 1.3 | 7.7 ± 0.5 | 25.0 ± 0.9 | −8.1 ± 2.2 | 15.5 ± 1.1 |
| Perchlorate | 1.96 ± 0.21* | −13.3 ± 1.4* | 10.2 ± 0.9 | 0.72 ± 0.06* | −14.6 ± 1.7* | 9.7 ± 1.1 | 23.3 ± 1.1 | −14.9 ± 2.7* | 14.5 ± 1.5 |
| Reference | 1.38 ± 0.05 | −17.2 ± 1.6 | 7.5 ± 0.2 | 0.49 ± 0.03 | −17.3 ± 1.6 | 7.5 ± 0.4 | 22.8 ± 1.4 | −24.1 ± 2.5 | 13.3 ± 1.1 |
| Caffeine | 1.58 ± 0.09* | −22.5 ± 1.8* | 7.8 ± 0.2 | 0.51 ± 0.02 | −21.6 ± 1.8* | 8.7 ± 0.6 | 24.0 ± 1.7 | −25.2 ± 2.1 | 12.9 ± 0.6 |
Equation (1) was fitted to values from each individual fibre and the parameters obtained were then averaged. The number of fibres was 8 and 10 for perchlorate and caffeine, respectively.
*
Significantly different from reference.