Figure 6. Effect of fatty acids on adult rat ventricular myocyte sarcolemmal membrane fluidity.

Ventricular myocytes plated on coverslips were incubated for 15 min with 1 μM TMAP-DPH at 37 °C. Cardiac myocytes were then transferred to a glass cuvette containing 20 μM fatty acids and the steady-state fluorescence anisotropy of TMAP-DPH was measured (as described in Methods). Data are presented as means ±s.e.m.**P < 0.01 compared with control. Abbreviations: Cont, control (no additions); SA, stearic acid (18:0); OA, oleic acid (18:1, n-9); LA, linoleic acid (18:2, n-6); ALA, α-linolenic acid (18:3, n-3); EPA, eicosapentaenoic acid (20:5, n-3); DHA, docosahexaenoic acid (22:6, n-3); B Alc, benzyl alcohol.