Table 2.

Inactivation parameters from least squares fit of eqn (2)

	Structure	Imax (pA)	V′(mV)	k (mV−1)
Control		−850 ± 92	−74.3 ± 1.5	5.2 ± 0.1
DHA 25 μm	(22:6, n-3)	−544 ± 88*	−96.6 ± 1.3‡	6.5 ± 0.2‡
Control		−1258 ± 107	−69.3 ± 2.1	6.5 ± 0.2
EPA 25 μm	(20:5, n-3)	−816 ± 106†	−86.5 ± 3.5†	7.4 ± 0.3‡
Control		−988 ± 103	−68.4 ± 2.0	5.8 ± 0.3
ALA 25 μm	(18:3, n-3)	−740 ± 83†	−88.9 ± 2.0‡	7.0 ± 0.2†
Control		−869 ± 105	−71.0 ± 2.8	6.3 ± 0.4
LA 25 μm	(18:2, n-6)	−898 ± 119	−77.3 ± 3.0‡	6.9 ± 0.4
Control		−901 ± 128	−76.0 ± 2.9	6.2 ± 0.3
OA 25 μm	(18:1, n-9)	−902 ± 156	−79.5 ± 2.3*	6.4 ± 0.1
Control		−974 ± 121	−73.7 ± 1.7	6.2 ± 0.2
SA 25 μm	(18:0)	−919 ± 105	−73.6 ± 2.2	6.9 ± 0.4
Control		−716 ± 63	−86.0 ± 1.8	8.4 ± 0.4
Benzyl alcohol (10 mm)		−140 ± 77†	−110.6 ± 3.8*	6.8 ± 1.4

^*P < 0.05

^†P < 0.01

^‡P < 0.001, significantly different from control (two-tailed Student's paired t test). Abbreviations: DHA, docosahexaenoic acid (n = 5); EPA, eicosapentaenoic acid (n = 10); ALA, α-linolenic acid (n = 6); LA, linoleic acid (n = 5); OA, oleic acid (n = 7); SA, stearic acid (n = 8). Benzyl alcohol (n = 3).