Figure 3. Time-dependent changes in the rate of the secretory response (dC_m/dt) with high [Ca²⁺]_i.

A, representative time-dependent changes in the rate of the secretory response (dC_m/dt) in control and in a CST-treated cell after cytosol dialysis with 1 μm $C_{\text{i}}^{2+}$. B, mean time-dependent changes in the rate of C_m change (dC_m/dt) determined at various time points after the start of cytosol dialysis with 1 μm ${\text{Ca}}_{\text{i}}^{2+}$ in control (•) and CST-treated cells (○). *Significant differences between the control and CST- treated cells (Student's t test, P < 0.01). Numbers adjacent to points indicate numbers of cells tested.