Table 1. Summary of the effects of chemical mediators on activation of afferent discharge and sensitization of responses to BK.
Basal discharge(%) | BK-induced discharge(%) | |
---|---|---|
Time control (n = 6) | −9.8 ± 3.9 | −7.7 ± 12 |
PGE2 (n = 6) | −2.4 ± 4.0 | +117 ± 48 |
Histamine (n = 4) | +29.9 ± 6.1 | +76.4 ± 25 |
Adenosine (n = 4) | +39.3 ± 4.4 | +88.7 ± 27 |
5-HT(n = 4) | +56.2 ± 18.3 | −13.8 ± 5.3 |
Dibutyryl cAMP (n = 4) | −5.1 ± 3.7 | +123.5 ± 28 |
Data are expressed as the percentage change (means ± s.e.m.s) for comparison, while statistical analysis was performed on the raw data presented in the text.