Figure 9. Electrical coupling between different B-cells.

A, glucose-induced electrical activity recorded with 10 mm glucose. Note that the membrane potential undergoes regular oscillations. The maximally negative interburst potential (V_i) and the plateau potential (V_p) are indicated by dotted lines. B, variations of the holding current recorded from the same cell. The variations of the holding current reflect bursts of action potentials in a neighbouring cell. The current levels corresponding to the repolarisation of the burst of action potentials (I_i) and the plateau (I_p) are indicated by dotted lines. C, stable holding current recorded at −70 mV in a non-B-cell in an intact islet exposed to 10 mm glucose.