Krig_Table 6.
Identification of genes responsive to loss of ZNF217
| RNAs responsive to loss of ZNF217* | A | B | C | 2 of 3 | 3 of 3 |
|---|---|---|---|---|---|
| RNAs upregulated by loss of ZNF217 | 462 | 402 | 540 | 288 | 106 |
| RNAs downregulated by loss of ZNF217 | 452 | 116 | 318 | 133 | 29 |
| ZNF217 targets upregulated by loss of ZNF217 | 43 | 61 | 77 | 42 | 18 |
| ZNF217 targets downregulated by loss of ZNF217 | 27 | 18 | 23 | 14 | 3 |
Up-regulated RNAs are identified as those having expression levels greater than 200 in the cells treated with siRNA to ZNF217 and a greater than 1.5 fold increase in expression after reduction of ZNF217; down-regulated RNAs are identified as those having RNA expression levels greater than 200 in the untreated samples and showing a greater than 1.5 fold decrease in expression after reduction of ZNF217. The intersection of the ZNF217 bound promoters and the upregulated RNAs are identified as ZNF217 targets upregulated by the loss of ZNF217 and the intersection of the ZNF217 bound promoters and the downregulated RNAs are identified as ZNF217 targets downregulated by the loss of ZNF217.