Table 3.

Single-channel conductance of recombinant and native 5-HT₃ receptors

5-HT3 receptor	Conductance (fS)	n
HEK 293
WT	390 ± 15	4
K4′R	478 ± 42	4
K4′Q	441 ± 35	4
K4′S	455 ± 28	4
K4′G	429 ± 32	4
SCG neurones†	3689 ± 357*	5

Data shown are the means ± s.e.m. of n independent experiments.

^*Significantly different from HEK 293 data (Student's t test, P < 0.05).

^†M. J. Gunthorpe & J. A. Peters, unpublished observations.