Table 2.

Changes of heart rate induced by different NO donors

Concentration	GTN	n	SNAP	n	DEA/NO	n
100 pm	—	—	−0.6 ± 1.0	7	−0.6 ± 0.4	15
1 nm	−0.2 ± 0.4	15	0.6 ± 1.2	7	1.1 ± 0.7	15
10 nm	0.5 ± 0.7	15	2.0 ± 1.0	15	1.8 ± 0.7	15
100 nm	0.3 ± 0.4	15	2.2 ± 0.9*	15	3.4 ± 1.2*	15
1 μm	0.2 ± 1.6	11	4.2 ± 2.0*	11	0.9 ± 1.1	8
5 μm	—	—	7.3 ± 3.3*	11	5.3 ± 2.1*	8
10 μm	0.1 ± 0.8	11	2.9 ± 1.1*	11	2.2 ± 0.8*	8
100 μm	1.6 ± 1.0	6	—	—	3.7 ± 3.3	8

Values are expressed as mean ± s.e.m. percentage change of heart rate related to the baseline value before drug infusion as observed in n different hearts

^*(P < 0.05 vs. baseline, paired t test).