A, Ic current recordings of a voltage-clamped oocyte in response to voltage pulses. B, MG channel currents in a cell-attached patch elicited in response to repetitive suction pulses at different membrane potentials. C, Ic reversal potential as a function of extracellular KCl activity (10 oocytes, 2 frogs). D, MG channel reversal potential as a function of KCl activity (10 inside-out patches). Points are means of measured reversal potentials. Some s.e.m. bars are concealed by the data points. The continuous lines were calculated according to the Goldman-Hodgkin-Katz (GHK) equation, with the relative permeabilities obtained by curve fitting (PCl/PK = 0.24 and PCl/PK < 0.01, for Ic and MG channel, respectively). The dotted lines were calculated according to the GHK equation, assuming an ideally cation-selective conductance.