Table 4.
Comparison of the properties of predicted whole-cell MG channel current and recorded whole-cell currents
| Current | PCl/PK | Gd2+ block | Rectification | PTBA/PK | Sensitivity to cell inflation |
|---|---|---|---|---|---|
| MG current | 0 | Yes | Strongly outward (ramp) | 0.05 | Increase |
| Ic | 0.24 | Yes | No (instantaneous) | 0.2 | Slight reduction |
| Ir | ∼1 | Yes | Strongly outward (ramp) | — | No |
| Ih | ∼1 | No | No (ramp) | ∼0.3 | No |
| Ishrink | ∼1 | No | No (ramp) | ∼1 | Significant reduction |
Rectification was judged by I–V relations measured either by voltage ramp (ramp) or steps (instantaneous).