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. 2000 Mar 15;523(Pt 3):685–696. doi: 10.1111/j.1469-7793.2000.t01-1-00685.x

Figure 6. Replacing EGTA in the recording pipette with BAPTA reduced the size of the slow component of the ATP response and eliminated the effect of capsaicin on the kinetics of ATP responses.

Figure 6

The records in A show the averaged, normalized current to ATP (10 μM) obtained when ATP was applied to cells (irrespective of capsaicin sensitivity) using an EGTA-based solution in the recording pipette compared to data obtained using a BAPTA-based solution. The data in C and E were obtained using a BAPTA-based recording solution and compare ATP responses obtained either before or after capsaicin application. Data in C are from capsaicin-sensitive cells and data in E are from capsaicin-insensitive cells. The data in B, D and F are plots of probability values obtained from unpaired t tests applied at 10 ms intervals comparing the current traces in A, C and E, respectively. Vh was −60 mV. The horizontal dashed lines in B, D and F indicate a value of P = 0.05.