Figure 5. Voltage dependence of the zero ACh concentration limits for the relaxation time constants.

A and B, plots of the zero ACh concentration limits for the fast and slow α2β2, α2β4, α3β2, α3β4, α4β2 and α4β4 relaxation time constants τ_f(0) and τ_s(0) versus membrane potential. Table 2 gives the slopes of the regression line (i.e. the voltage dependence of τ(0)). A, the extrapolated τ_f(0) at 0 mV was 6, 5, 7, 35, 31 and 42 ms for the α2β2, α3β2, α4β2, α2β4, α3β4 and α4β4 subtypes, respectively. B, the extrapolated τ_s(0) at 0 mV was 32, 41, 40, 138, 234 and 398 ms for the α2β2, α3β2, α4β2, α2β4, α3β4 and α4β4 subtypes, respectively. The error bars are ±s.e.m..