Table 2.
Gaseous composition of the blood perfusing the isolated carotid body chemo receptors of the recipient animals under control conditions (normoxic recipient blood) and during three levels of hypoxia (hypoxic isocapnic blood from the donor animal)
| Recipient animal, carotid body perfusate | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Spontaneously breathing (10/6) | Artificially ventilated (9/6) | Artifically ventilated cervical vagotomy (16/8) | |||||||
| Donor ventilating gas | PO2 (mmHg) | PCO2 (mmHg) | pH | PO2 (mmHg) | PCO2 (mmHG) | pH | PO2 (mmHg) | PCO2 (mmHg) | pH |
| Normoxia | |||||||||
| 30% O2 in N2 | 125 ± 16·4 | 45·8 ± 2·8 | 7·319 ± 0·049 | 118·2 ± 18·6 | 40·0 ± 5·1 | 7·393 ± 0·042 | 119·1 ± 14·2 | 40·5 ± 4·5 | 7·40 ± 0·051 |
| Hypoxia | |||||||||
| 16% O2 in N2 | 60·7 ± 9·0 | 41·6 ± 2·5 | 7·350 ± 0·037 | 58·9 ± 3·7 | 42·8 ± 5·1 | 7·352 ± 0·046 | 50·6 ± 5·9 | 42·7 ± 5·1 | 7·345 ± 0·042 |
| 12·5% O2 in N2 | 39·9 ± 8·7 | 41·0 ± 3·8 | 7·350 ± 0·038 | 44·8 ± 3·1 | 39·3 ± 4·0 | 7·374 ± 0·048 | 37·1 ± 6·4 | 42·7 ± 5·6 | 7·352 ± 0·05 |
| 5·5% O2 in N2 | 23·2 ± 3·5 | 40·3 ± 3·5 | 7·366 ± 0·04 | 21·8 ± 2·1 | 38·8 ± 4·7 | 7·390 ± 0·063 | 19·5 ± 3·5 | 40·5 ± 4·7 | 7·401 ± 0·04 |
Values are means ± s.d. Numbers in parentheses are the number of sets of observations/number of recipient animals in each group of experiments: spontaneously breathing, artificially ventilated and artificially ventilated combined with division of both cervical vagosympathetic nerves.