Figure 5. Veratridine- and monensin-induced overexpression of the Na⁺,K⁺-ATPase α3 subunit.

A, quantification of the subcellular distribution of the Na⁺,K⁺-ATPase α3 subunit after a 1 h exposure to 50 μM veratridine using confocal immunofluorescence microscopy. B, subcellular distribution of the Na⁺,K⁺-ATPase α3 subunit after a 1 h exposure to 50 μM monensin as determined with confocal immunofluorescence scanning. C, fluorescence images of two representative neurones – control (left) and exposed to veratridine (right). D, 3D intensity profiles of the same neurones as in C. Note the higher content of the Na⁺,K⁺-ATPase α3 subunit in the veratridine-treated neurone.