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. 2000 Jun 15;525(Pt 3):761–770. doi: 10.1111/j.1469-7793.2000.00761.x

Figure 4. Shear stress-dependent downregulation of endothelin-1 (ET-1) peptide release.

Figure 4

The effect of shear stress on ET-1 protein expression was quantified as ET-1 peptide release into the cell culture medium (in percentage of internal control without shear stress). The ET-1 release of HUVEC is downregulated by long-term (24 h) shear stress in a dose-dependent manner. Values are given as means ±s.e.m.; n= 6; * P < 0.05 vs. static control (con) (static condition: open bar, shear stress: hatched bars).