Skip to main content
. 2000 Jun 15;525(Pt 3):707–719. doi: 10.1111/j.1469-7793.2000.t01-1-00707.x

Table 2.

[Ca2+]L oscillation frequencies determined at 1 or 10 μM InsP3 in various intracellular-like media and in the presence of mitochondrial inhibitors

InsP3 alone + FCCP–oligomycin + Ruthenium Red



Intracellular medium 1 μM InsP3 10 μM InsP3 P 1 μM InsP3 10 μM InsP3 P 1 μM InsP3 10 μM InsP3 P
Chelex 5.2 ± 1.7 (7) 4.8 ± 1.6 (14) >0.5
100 μM EGTA 6.4 ± 2.3 (8) 6.2 ± 1.6 (15) >0.7
EGTA-citrate 2.9 ± 1.4 (15) 4.7 ± 1.6 (16) <0.002 4.7 ± 1.3 (5) 4.4 ± 1.0 (7) >0.6 4.5 ± 1.1 (4) 3.7 ± 1.0 (5) >0.3
EGTA-succinate 3.1 ± 1.6 (6) 5.8 ± 1.8 (8) <0.01
EGTA-pyruvate/malate 2.3 ± 0.7 (5) 3.9 ± 1.6 (7) <0.05

Oscillation frequencies are given in spikes min−1. Numbers in parentheses indicate the number of experiments performed under each condition. P values indicate the levels of significance with respect to differences in oscillation frequency at 1 and 10 μM InsP3 in a given medium using Student's nonpaired t test. Bold type highlights values considered to be significantly different.