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Effects of NO–adenylate cyclase–cAMP signalling on basal ICa,L amplitude in cells plated on glass or laminin
| Glass | (n) | Laminin | (n) | |
|---|---|---|---|---|
| Spermine–NO (200 μm) | 163 ± 37 | (7) | 57 ± 21* | (7) |
| Milrinone (10 μm) | 66 ± 15 | (5) | 28 ± 7* | (5) |
| 8-PTC-cAMP (100 μm) | 35 ± 7 | (4) | 40 ± 6 | (3) |
| IBMX (100 μm) | 619 ± 104 | (6) | 263 ± 52* | (6) |
| Forskolin (1 μm) | 230 ± 35 | (10) | 127 ± 25* | (9) |
Values indicate percentage changes compared with controls; n, total number of cells studied.
P = 0·05.
