Figure 7. Model-simulated I_HERG in the absence and presence of low (10 μm) and high (2 mm) Ba²⁺ concentrations.

Applied pulse protocols were identical to those used experimentally, i.e. -80 mV holding potential and 2 s depolarizations to the test voltages followed by return to the holding potential. Note the similarity in responses to experimental recordings (Fig. 1A).