Table 2. Effects of peptide hormones and ouabain on 86Rb uptake in rat soleus muscle.
| Additions | 86Rb uptake (nmol (g wet wt)−1 min−1) | P |
|---|---|---|
| 15 min incubation | ||
| Control | 504 ± 11 (8) | — |
| Amylin (10−7m) | 623 ± 20 (8) | <0.05 |
| Insulin (7 × 10−7m) | 643 ± 15 (8) | <0.05 |
| Insulin + amylin | 719 ± 16 (8) | <0.05 |
| Ouabain (10−3m) | 257 ± 4 (4) | <0.05 |
| Ouabain + amylin | 245 ± 12 (4) | <0.05 |
| Ouabain + insulin | 261 ± 8 (4) | <0.05 |
| Ouabain + insulin + amylin | 249 ± 4 (4) | <0.05 |
| 10 min incubation | ||
| Control | 537 ± 26 (8) | — |
| CGRP (10−7m) | 715 ± 20 (8) | <0.05 |
| Substance P (10−7m) | 547 ± 14 (8) | n.s. |
| Control | 595 ± 27 (12) | — |
| IAPP (10−7m) | 596 ± 16 (12) | n.s. |
| Control | 547 ± 44 (4) | — |
| Adrenomedullin (10−7m) | 523 ± 15 (4) | n.s. |
Experimental conditions as described in the legend to Fig. 4, but using incubation periods of 15 or 10 min.86Rb uptake values are given as means ±s.e.m.with the number of observations in parentheses. The significance of the difference between control and experimental values was assessed by multiple comparison procedures (Tukey test).