Figure 4. Time-dependent effect of PKC activation on cation entry.

A, platelets were preincubated at 37 °C for 5 or 30 min in the absence (Control) or presence of PMA (1 μm). Cells were then treated with TG (200 nM) and 3 min later SrCl₂ (final concentration, 300 μm) was added (n = 6). B, platelets were preincubated at 37 °C for 5 or 30 min in the absence (Control) or presence of OAG (100 μm). Cells were then treated with TG (200 nM) and 3 min later SrCl₂ (final concentration, 300 μm) was added (n = 6).