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. 2008 Feb 10;4(4):209–225. doi: 10.1900/RDS.2007.4.209

Figure 4. A variety of pancreatic transcription factors are involved in PDX-1 gene expression.

Figure 4

Alignment of the mouse and human PDX-1 gene sequences revealed three conserved regions (Area I, II and III) which harbor binding sites of various transcription factors such as HNF-3β, HNF-1α, PDX-1, Pax6, MafA and Ptf1a.