Fig. 5. Sensitivity of FCBPs to immunosuppressant drugs.
PPI-ase activity of the recombinant enzymes from T. gondii and F. johnsonii was determined in the presence of the indicated concentrations of CsA (gray bars) or ethyl-FK506 (black bars) or a mixture of the two (striped bars). The uninhibited activity of the corresponding enzymes (white bars) was taken as 100. Results represent an average of three experiments with mean ± S.E.