Figure 1. HIV infection in human DRG cells from patients with history of HIV-peripheral neuropathy.
A) Macrophage infiltration of the DRG visualized with anti-CD68 immunostaining and counterstained with Cresyl-violet
B) Distribution of HIV-p24 antigen (red) in the DRG as visualized by confocal microscopy. The HIV-p24 was localized in the perineuronal compartment and within cells with macrophage morphology. Schwann cells and their processes (green) visualized with anti-GFAP antibodies lack any co-localization with HIV-p24.