Mitochondrial free radical production and membrane potential was measured in human DRG cell bodies following treatment with supernatants from THP-1 cells infected with HIV-1IIIB and MDM infected with HIV-1Ba-L.
A) Increase in DHR intensity is shown as standardized data. * Supernatant from infected monocytic cells versus the matched control, p < 0.05. Each data bar represents approximately 100 analyzed neurons
B) Mitochondrial membrane potential (red/green ratio) is shown as standardized data. * Supernatant from infected monocytic cells versus the matched control, p < 0.05. Each data bar represents at least 150 analyzed neurons.