Table 1.
IL-1α, ER/PR, and lymph node metastasis in primary breast cancers
| Tumor no. | IL-1 | ER | PR | Node status |
|---|---|---|---|---|
| T101 | 2+ | — | — | 0/21 |
| T102 | 2+ | — | — | 1/17 |
| T103 | 15+ | — | +/− | 22/22 |
| T108 | + | 50% | — | 0/1 |
| T111 | 2+ | 70% | 80% | 1/14 |
| T114 | + | + | + | 0/20 |
| T115 | + | 80% | 80% | 7/17 |
| T116 | + | — | — | 0/19 |
| N117 | + | — | — | |
| T120 | + | 30% | 60% | 0/18 |
| N121 | + | |||
| T124 | 10+ | — | NA | 2/20 |
| N125 | 3+ | |||
| T126 | 6+ | + | + | 13/20 |
| N127 | 3+ | |||
| T128 | 2+ | — | — | 1/1 |
| N129 | 7+ | |||
| T130 | + | + | + | 0/20 |
| N131 | + |
Quantitation is based on densitometric scanning of autoradiograms, and the values were corrected for the difference in 36B4 level. A value of + was assigned to the sample that displayed least IL-1α-amplified product. Percentage of cells that stained positive for ER and PR is given for tumors that are heterogeneous. Tumor that stained weakly for PR is indicated as +/−. Positive lymph node versus number of lymph nodes examined is also shown. NA, not available.