Table 1.

Prion infection increased the amounts of free cholesterol in neuronal cell lines. The amounts of total cholesterol, free cholesterol and esterified cholesterol (ng cholesterol/mg protein) in extracts from prion infected neuronal cells (ScN2a or ScGT1 cells) compared with their non-infected counterparts (N2a or GT1 cells). Values shown are the mean ± SD from 11 samples.

	Cholesterol (ng/mg protein)
			Esterified
	Total (mean ± SD)	Free (mean ± SD)	Mean ± SD	Percentage
N2a	472 ± 47	384 ± 37	87 ± 19	18 ± 4
ScN2a	525 ± 34	473 ± 41	52 ± 14	10 ± 3
GT1	453 ± 72	368 ± 59	85 ± 28	19 ± 5
ScGT1	542 ± 44	500 ± 54	42 ± 14	8 ± 3