Table 1.
Association of the rlrA islet with serotypes and PFGE clusters
| Serotype | OR (95% CI)a | p | STs in PFGE clusterb | OR (95% CI) | p |
| 1 | 0.22 (0.07 – 0.53) | 0.0011 | [ST306 + ST228] | 0.079 (0.01 – 0.59) | 0.0007 |
| 3 | NSc | [ST1220 + ST260] + [ST1230 + ST180] | 0.06 (0.01 – 0.44) | < 10-4 | |
| 4 | 12.74 (5.05 – 32.12) | < 10-4 | ST1221 | 80.26 (4.72 – 1363.4) | < 10-4 |
| ST247 | 30 (3.8 – 236.84) | < 10-4 | |||
| 6B | 7.44 (2.29 – 24.16) | 0.0005 | ST1224 + ST273 | 47.33 (2.7 – 830.37) | < 10-4 |
| 7F | 0 (0 – 0.61) | 0.0052 | ST191 | 0 (0.0 – 0.70) | 0.0089 |
| 8 | 0 (0 – 0.37) | 0.0002 | ST53 | 0 (0.0 – 0.57) | 0.0057 |
| 9V | 14.36 (4.76 – 43.33) | < 10-4 | [ST156 + ST557 + ST644 + ST1225] | 16.76 (4.80 – 58.54) | < 10-4 |
| 12B | 0 (0 – 0.70) | 0.0089 | NSc | NSc | |
| 14 | 16.13 (8.50 – 30.63) | < 10-4 | [ST156 + ST557 + ST790] | 212.4 (28.89 – 1561.8) | < 10-4 |
| 23F | 0 (0 – 0.44) | 0.0006 | ST338 + ST1371 | 0 (0.0 – 0.57) | 0.0057 |
aAn OR of > 1 indicates increased proportion of rlrA positive isolates whereas OR of < 1 indicates decreased proportion of rlrA positive isolates. Only statistically significant results (FDR < 0.05) are presented.
bSTs in PFGE clusters with a Dice similarity coefficient of > 80%. Brackets indicate STs that belong to the same lineage, as defined by eBURST analysis with the complete S. pneumoniae database available at spneumoniae.mlst.net. Only statistically significant results (FDR < 0.05) are presented.
cNS – not significant