Table 2.

 Effects of statins on lipid concentrations and renal function in patients with chronic kidney disease

Outcome	No of trials (No of patients)	Weighted mean difference (95% CI)	Heterogeneity (I2; %)
Total cholesterol (mg/dl)*	42 (6390)	−42.28 (−47.25 to −37.32)	94.9
LDL cholesterol (mg/dl)*	39 (6216)	−43.12 (−47.85 to −38.40)	94.1
HDL cholesterol (mg/dl)*	40 (5621)	0.41 (−0.78 to 1.60)	94.4
Triglycerides (mg/dl)†	39 (5569)	−23.71 (−33.52 to −13.90)	89.5
Glomerular filtration rate (ml/min or ml/min/1.73 m2)	11 (548)	1.48 (−2.32 to 5.28)	62.0
Urinary protein excretion (g/24 h)	6 (311)	−0.73 (−0.95 to −0.52)	58.6

HDL=high density lipoprotein; LDL=low density lipoprotein.

*Multiply by 0.0259 to convert to mmol/l.

†Multiply by 0.01 to convert to mmol/l.