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. 2008 Feb 18;205(2):423–435. doi: 10.1084/jem.20071489

Figure 5.

Figure 5.

MCMV infection results in the persistence of the EGL and decreased thickness of the IGL and ML in MCMV-infected mice on PN day 10. (A) Immunofluorescent staining of frozen section from representative saggital sections of cerebellum from control and infected mice. Purkinje neurons (PC; green) were stained with calbindin and developed with FITC anti-MIgG. Nuclei were stained with TOPRO III (blue). Note the differences in the thickness of the EGL and ML between sections from the MCMV and control animals. Also note the loss of arborization of the Purkinje dendrites in MCMV-infected as compared with control animals. Bar, 100 μm. (B) Morphometry of the EGL, ML, and IGL was performed on saggital sections, and each data point was derived from six control and infected mice per time point as described in Materials and methods.