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. 2008 Feb 18;205(2):331–337. doi: 10.1084/jem.20070906

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Copyright © 2008, The Rockefeller University Press

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Figure 2. — Mesenchymal cells from Tnf^ΔARE mice are activated before disease onset. (A) Representative gelatin zymogram showing MMP9 and MMP2 secretion either from SFs (left) or IMFs (right) derived from WT and Tnf^ΔARE/+ 4-wk-old mice. (B) Representative semiquantitative RT-PCR for MMP3 and TIMP1 expression in SFs (left) or IMFs (right) derived from WT and Tnf^ΔARE/+ 4-wk-old mice. WT cells treated with TNF were used as a positive control in A and B.