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. 2008 Feb 18;205(2):395–408. doi: 10.1084/jem.20071548

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Copyright © 2008, The Rockefeller University Press

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Figure 3. — HDC^−/− mice are resistant to lethal infection by two Pb strains of parasites. Mortality (A and C) and parasitemia (B and D) were recorded for wild-type C57BL/6 mice (squares) or HDC^−/− mice (diamonds) infected via mosquito bites with Pb NK65 (A and B) or with Pb ANKA (C and D). Groups consisted of 10 mice. Differences in parasitemia are significant at each time point from day 12 until day 19 (P < 0.001) in B but not in D, and data are shown as means ± SD. Three independent experiments were performed with similar results.