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. Author manuscript; available in PMC: 2009 Mar 5.
Published in final edited form as: FEBS Lett. 2008 Feb 13;582(5):810–814. doi: 10.1016/j.febslet.2008.02.008

Fig. 3.

Fig. 3

Localization of HMGA1-responsive region in the hNOS2 promoter. Luciferase reporter plasmid constructs (hNOS2 −8296, −5496, −3658, and −2950) were transiently co-transfected (500 ng/well) with an expression plasmid for dnHMGA1 (500 ng/well) or empty vector into A549 cells. Cells were exposed to CM or vehicle, and then harvested for luciferase activity. Promoter activity was plotted as fold induction of hNOS2 promoter activity from cells receiving no CM and no dnHMGA1. n=6 in each experiment. *, increase (p < 0.05) versus no CM and no dnHMGA1; † decrease (p < 0.05) versus no CM and no dnHMGA1; NS, not significant.