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. 2008 Apr 2;3(4):e1919. doi: 10.1371/journal.pone.0001919

Figure 1. Evaluation of the structure and total DNA content of hippocampal pyramidal tissues in P3 progeny of saline-treated and cocaine-treated mice.

Figure 1

(a) Typical micrograph of HistoGene-stained coronal section through the hippocampus of a P3 Saline pup. (b) Micrograph of a comparable section from an age-matched offspring of a cocaine-treated mother. (c) Relative amounts of total DNA content between the offspring of saline-treated and cocaine-treated mothers at P3 and P30. Horizontal bars show mean difference in DNA content between Cocaine and Saline groups at each age, while vertical bars show the SEM (n  = 10/group/age). For either age group, the inter-sample ranges of coefficient of error (CE) values are provided at the bottom of the chart. C1, C2, C3, hippocampal regions; DG, dentate gyrus. Note the absence of detectable histological differences between micrographs a and b.